When Is a “Generic” Medication Not Really a Generic? Confusion About Medication Products Containing the Same Active Ingredient
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Glazov, What Color is Your Brain?

Psychopharmacology
When Is a “Generic” Medication Not Really a Generic? Confusion About Medication Products Containing the Same Active Ingredient

Journal of Psychosocial Nursing and Mental Health Services   Vol. 48 No. 2   February 2010

By Robert H. Howland, MD

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ABSTRACT

The distinction between pharmaceutical equivalent and pharmaceutical alternative drug products can lead to considerable confusion, especially with the proliferation of various branded, alternative, and generic medications that contain the same active ingredient. To illustrate this problem, four examples of medication products containing the active ingredients paroxetine, venlafaxine, bupropion, and valproate will be described. Understanding these differences is important for nurses providing patient care. Only generic drugs can be freely substituted for a brand-name product. Switching to a pharmaceutical alternative requires a change in prescription. Finally, the use, labeling, and cost of branded, alternative, and generic medications may be different.

AUTHOR

Dr. Howland is Associate Professor of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, Pennsylvania.

The author discloses that he has no significant financial interests in any product or class of products discussed directly or indirectly in this activity, including research support.

Address correspondence to Robert H. Howland, MD, Associate Professor of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, 3811 O’Hara Street, Pittsburgh, PA 15213; e-mail: HowlandRH@upmc.edu.

Posted: January 22, 2010

doi:10.3928/02793695-20100108-04